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This change makes the molecule too hydrophilic to cross BBB, therefore high dose is needed for CNS application [16]
[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Andreadou I., Schulz R., Papapetropoulos A., Turan B., Ytrehus K., Ferdinandy P., Daiber A., Di Lisa F
The researchers concluded that AOD-9604 represents a promising fat-reducing alternative to growth hormone therapy without its associated metabolic risks, particularly regarding glucose regulation and IGF-1 elevation
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