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Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

This is usually an indication that you have a methylation defect and need to slow down on the amount of B12 you are taking

If you plan to reconstitute within a few weeks, refrigeration at 2 to 8 degrees Celsius (36 to 46 degrees Fahrenheit) is sufficient

If you are over, push a tiny bit back into the vial

Its premium formula includes methylcobalamin and adenosylcobalamin, the most bioavailable forms of B12

Use an insulated medical cooling case with ice packs wrapped in a towel to maintain temperatures between 3646F