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The component nuclear pore protein Seh1 plays a role in protecting the homeostasis of SCs by maintaining genomic integrity, and it has been shown that interactions following Seh1 ablation trigger ZBP1-dependent necroptosis in SCs leading to peripheral neuropathy (128), however, whether HG has an effect on this link is not clear

von Otter et al

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Current clinical management primarily relies on immunosuppression therapy

Australias TGA Medical Devices The Therapeutic Goods Administration (TGA) is the unit of the Australian governments Department of Health and Aging that oversees medical device regulation in Australia