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The protein level of -catenin and its downstream targets, such as Cyclin D1, c-MYC, and PCNA, increased as assessed by WB

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T.Ruiz-LinaresM

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Cancer genes and the pathways they control

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This product is designated FOR RESEARCH USE ONLY (RUO)

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In addition to cell cycle arrest, 1D228 reversed the EMT by upregulation of E-cadherin expression and downregulation of N-cadherin, which significantly blocked the tumor cell migration

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Zhou et al., 2021[169]

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