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Pregnancy Adequate and well-controlled studies have not been done in pregnant women

a C-terminal exendin-4 extension sequence (CEX) succeeds agonism at all three receptors 10-fold greater than native hormones (155)

The STEP 4 withdrawal trial demonstrated that continued Semaglutide therapy was needed to maintain weight loss, as patients switched to placebo regained weight over 48 weeks (Rubino et al., JAMA 2021

This sequence is a general laboratory reference for in vitro assay preparation and is provided for research purposes only

2015 Jun;48(6):e11-26

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