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In some parts of China (e.g., Keshan), the intake was only 314 g/day (56, 57), and the endemic Se deficiency appeared in the form of chronic osteochondropathy (KashinBeck disease) and chronic cardiomyopathy (Keshan disease), which are now preventable through Se supplementation (71, 72)
Another important aspect of DSF's biological effects is its ability to react with cysteine residues of proteins and enzymes such as ALDH, P-gp, MGMT, NF-B, and others

Coll RC, Schroder K, Pelegrn P
