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Unusually for a peptide it is stable in gastric acid, which is why it has been studied across both systemic and gastrointestinal injury models

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S100A7 is an EF-hand type calcium-binding protein with a molecular weight of 11.4 kDa localized in the cytoplasm of keratinocytes and distributed at the cell periphery in terminally differentiated keratinocytes (68)

Its resistance to the pH changes and general hydrolysis found in the stomach translates into better stability in sterile solution as well [4]