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However, the consistency of these associations remains limited, and clinical guidelinessuch as those issued by the Clinical Pharmacogenetics Implementation Consortium (CPIC)do not currently recommend the use of HTR2A as a standalone clinical biomarker (Hicks et al., 2015)

doi: 10.1016/s0140-6736(18)32167-6 [DOI] [PubMed] [Google Scholar] 202

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In the preceding decade, translational therapies targeting cancer metabolism have seen only limited progress

Thus, to execute cell death, erythrocytes can rely only on the retained components of the cell death machinery inherited from the erythroid precursors