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Q., Chiu, P., Ko, B

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"BPC" stands for "Body Protection Compound." In preclinical work it is proposed to act through several overlapping pathways, including promotion of new blood-vessel growth (angiogenesis), modulation of nitric-oxide signaling, and anti-inflammatory activity, rather than through one well-defined receptor mechanism the way a conventional small-molecule drug does

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All of these factors collectively lead to NP patients needing higher doses of morphine than non-NP patients to achieve effective analgesia

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[DOI] [PubMed] [Google Scholar] 78.Lee C.Y., Perez F.M., Wang W., Guan X., Zhao X., Fisher J.L., Guan Y., Sweitzer S.M., Raja S.N., Tao Y.X

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Patients have experienced a substantial improvement in quality of life

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