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Evidence (sorafenib): A phase III, randomized, double-blind, placebo-controlled study (DECISION [NCT00984282]) evaluated sorafenib in patients with progressive, iodine-refractory, differentiated thyroid cancer.[21] This trial included 417 patients with locally advanced or metastatic RAI-refractory thyroid cancer (papillary, follicular [including Hrthle cell], and poorly differentiated tumors) whose disease had progressed within the past 14 months

This inhibitory effect observed in both experimental conditions may be due to the fact that glutathione reacts with the orthodiquinones produced by the enzymatic oxidation of hydroxycinnamic acids to form the grape reaction product (GRP) [23, 31, 55, 56]

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Horowitz stated, I also have contacted my state and federal representatives about the article and explained the urgent need to do a randomized, controlled study to evaluate the efficacy of the treatment protocols described in the paper. TOUCHED BY LYME is written by Dorothy Kupcha Leland, LymeDisease.orgs Vice-president and Director of Communications