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Currently undergoing Phase 1 clinical trial evaluation (ClinicalTrials.gov Identifier: NCT04167137) in patients with advanced solid tumors and lymphomas, the engineered bacterial strain SYNB1891 represents a novel approach to targeting the tumor microenvironment

Int Immunopharmacol 2022;113:109422

Tissue preparation Mouse L5 DRGs were dissected, fixed with 4% paraformaldehyde (Affymetrix, OH, USA), washed with phosphate buffered saline (PBS), impregnated with 15% sucrose, and then with 30% sucrose, each overnight at 4C except for the washing step

PLoS One 9, e92094 Gavalda, S., Bardou, F., Laval, F., Bon, C

and 5) also propose several future research perspectives for EGT