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Amylin receptor activation in the area postrema and lateral parabrachial nucleus reduces the rewarding value of food, decreases meal size, and promotes earlier satiation

LapennaDde GioiaSCiofaniGMezzettiAUcchinoSCalafioreAMet alGlutathione-related antioxidant defenses in human atherosclerotic plaques

10.1016/j.cej.2020.126004 322 YangX.JiaH.XingW.LiF.LiM.SunK.et al (2019)

doi: 10.1016/j.taap.2025.117266 118 WeidleUHBirzeleFKrgerA

Neuropsychopharmacology 40 , 113128 (2015)

Biological Activity Cagrilintide and semaglutide, when co-administered, produce synergistic reductions in bodyweight (up to ~1517% over 2032 weeks in clinical trials) and significant improvements in glycemic parameters, including HbA1c and fasting glucose