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Wiley, C

Introduced in the 1980s, organotypic slice cultures were traditionally cultured using the roller-tube method but have since been optimized to culture via the air-liquid interface method, which allows slices to simultaneously receive nutrients from the culture medium and humidified air, facilitating long-term viability (Ghwiler, 1981

Clinical and preclinical signals collectively support testing neurotrophin-targeted strategies to recalibrate myeloid composition, enhance antigen presentation, and restore T-cell access to tumor beds

These effects are observed even in rats deficient in GH or vasopressin.76 Uni-Nx-induced renal enlargement occurs similarly in both normal and GH-deficient rats when fed a diet with moderate protein content

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NA can instead be transported by SLC5A8 and SLC22A13 74,75 , while SLC7A5 and SLC36A4 are required for uptake of Trp 71,72