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Rogan, Eleanor G., et al

Because there hasnt been much research done focusing on safety of L-theanine supplementation during pregnancy, its best for pregnant women to avoid taking L-theanine (although drinking one to two cups of green tea during pregnancy is considered safe for most women)

It has been demonstrated that xanthine oxidase activity is increased in the placenta of women affected by HDP

189 MacfarlaneS

74 Salvianolic acid A reduces intracellular ROS production, inhibits TGF-1 and EndMT, and counters PVR by activating the Nrf2/HO-1 pathway

However, a limitation of that study was that the number of subjects considered was very small [130]