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Omega-3s/Zinc: High doses may interact with medications or cause GI effects
Additionally, the outer membrane protein of Akkermansia muciniphila , Amuc_1000*, upregulates Cldn3 and Ocln at least partially through the activation of TLR2 signaling (78)

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(9) favorable modulation of the autonomic nervous system [40], leading to heightened norepinephrine synthesis and parasympathetic orchestration [120122]

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Other known drug substrates for CYP2D6 are debrisoquine, dextromethorphan, and the tricyclic antidepressant nortriptyline (Figure 5) [38]
