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The honest answer is: we do not know

Clinical laboratories generally define vitamin B12 deficiency as a serum level below 148 pmol/L (approximately 200 pg/mL)

Pilitsi, E

Some users also report mild pain after injecting

Fatigue can have many causesincluding poor sleep, stress, thyroid disorders, or iron deficiencythat B12 injections cannot address

When levels fall below the clinical threshold, men develop symptoms of hypogonadism that can significantly impact quality of life
