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they assessed the effectiveness of the frailty using physical function, body composition and physical and cognitive function, with less focus on frailty biomarkers
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However, DMF is able to raise glutathione levels also when the rate-limiting enzyme of glutathione synthesis, i.e., glutamate-cysteine ligase, is inhibited, thanks to the Nrf2-mediated induction of glutathione reductase that enhances the molecule recycling (57)
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10.1002/adfm.200902043
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