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Description
Additional strategies aim to disrupt mitochondrial function through VDAC1 blockade or to reduce tumor hypoxia using hypoxia-activated prodrugs, hyperbaric oxygen therapy, and oxygen-transporting agents

it's encoded within the mitochondrial DNA

10.1093/jxb/erad018 52 ItoT.KitaiwaT.NishizonoK.UmahashiM.MiyajiS.AgakeS.et al (2022)

This may be linked to the maintenance of GGH activity at a low pH and temperature [67]

This is still speculative for clinical endometriosis

reconstruction matrix, 512
