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Epitalon was administered for 30 or 42 days
doi:10.1006/jmbi.1998.1927
Though this is speculative rather than evidence-based
Popovich, and Mark A
[5] Who Is Most at Risk of B12-Related Acne

This may include targeted nutritional strategies, supplementation, and medical interventions aimed at improving insulin sensitivity, reducing oxidative stress, and supporting cellular repair processes alongside GHK-Cu therapy