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Description
Diabetologia 58 (4), 799808
Delvin, A
68 Detailed analysis suggests a multipronged effect of the changes in intestinal claudin-1 expression, including mucosal barrier properties (mucin-2 expression) and epithelial homeostasis
The inserted amino acid in the QueD2 Cx 4 HGH motif displaces the Cys nucleophile far from the catalytic site, while shifting the metal coordinating HGH motif (His28 and His30 in Ab QueD2) further into the 2 strand relative to Ec QueD
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A healthcare provider can diagnose properly and recommend appropriate treatment options, including therapy, medication, or a combination
