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Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet
doi: 10.1200/jco.2017.72.7735

Studies confirm 50% drops by midlife, linking to aging symptoms.[1][9] Restoring NAD+ has been shown in animal studies to improve lifespan and healthspan, with human trials indicating benefits in muscle function and cognitive performance

Skin dysesthesia is one signal that has since made it onto the label
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