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doi: 10.1038/s41575-018-0054-1 229 ZhangSLiangYYaoJLiDFWangLS

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Brucine, a weak alkaline indole alkaloid extracted from the seeds of Strychnos nux-vomica, can increase the nuclear transport of ATF3 by activating ER stress, promoting ferroptosis in GBM [106]

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43(6), 667669 Schmitt B, Vicenzi M, Garrel C, Denis FM

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These could include symptoms such as itching, a rash/hives, swelling especially around the face or throat, or difficulty breathing

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Cognitive decline and Alzheimers disease Alzheimers disease (AD) is a form of dementia characterized by extracellular deposition of -amyloid plaques, intracellular formation of neurofibrillary tangles, and neuronal loss, eventually leading to brain atrophy and cognitive impairment in affected individuals (57)

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Monitor patients for conditions indicative of diversion or progression of opioid dependence and addictive behaviors

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