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doi: 10.1038/s41575-018-0054-1 229 ZhangSLiangYYaoJLiDFWangLS

Brucine, a weak alkaline indole alkaloid extracted from the seeds of Strychnos nux-vomica, can increase the nuclear transport of ATF3 by activating ER stress, promoting ferroptosis in GBM [106]

43(6), 667669 Schmitt B, Vicenzi M, Garrel C, Denis FM

These could include symptoms such as itching, a rash/hives, swelling especially around the face or throat, or difficulty breathing

Cognitive decline and Alzheimers disease Alzheimers disease (AD) is a form of dementia characterized by extracellular deposition of -amyloid plaques, intracellular formation of neurofibrillary tangles, and neuronal loss, eventually leading to brain atrophy and cognitive impairment in affected individuals (57)

Monitor patients for conditions indicative of diversion or progression of opioid dependence and addictive behaviors
