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Curcumin-treated cells showed elevated ROS, MDA and Fe2+ levels, decreased SOD, GSH and GPX4 levels, and increased nuclear NRF2 level and nuclear translocation, and HMOX1 expression, suggesting that curcumin activated the NRF2/HMOX1 pathway to promote ferroptosis, thereby inhibiting lung cancer cell malignant progression

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7g, h), and similar trends were observed under additional UPS-inducing conditions, including STX5 or SAR1-T39N overexpression and thapsigargin treatment (Fig

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The Discovery and Significance of a Human Copper-Binding Peptide The story of GHK-Cu begins in 1973, when Dr