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Have a history of pancreatitis as there is a slight increased risk of developing pancreatitis on this medication Have gastroparesis due to it slowing down gastric emptying which can worsen gastroparesis Have hypertriglyceridemia, or extremely high triglyceride levels As with other agents in this class, tirzepatide has a boxed warning regarding rodent thyroid C-cell tumor findings and the uncertain relevance to humans

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They may use lower-grade raw materials, compound in non-sterile environments, skip endotoxin testing, and have no regulatory body checking their work

It works best as part of a comprehensive protocol with proper diagnosis, dosing, and follow-up