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Carolyn Dean MD ND.

Losing too much of it may compromise metabolic flexibility and longevity

GLP-1 RAs provide sustained central and peripheral GLP-1R activation that blunts appetite via hypothalamusvagusNTS circuits, improves metabolic health, and may reduce alcohol and other substance-related craving and reward signals.

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Semaglutide (Ozempic) stimulates insulin production, helping balance blood glucose levels and reducing appetite