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The pathophysiologic mechanisms underpinning S-AKI are complex, and recent studies have shown that acute tubular necrosis, oxidative stress (7), mitochondrial dysfunction, inflammatory responses (8), microvascular dysfunction (9), and ischemia are involved (Figure 1)

Eur J Intern Med 14(8):459469 Gupta MK, Qin R-Y (2003) Mechanism and its regulation of tumor-induced angiogenesis

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Both cysteine and glutathione react with NO via their SH groups to form SNOs, molecules that are more stable than NO itself

We did not find that QT alone ameliorates the Ca 2+ transport in the intestine, but we demonstrated that QT blocks the inhibition of the intestinal Ca 2+ absorption caused by MEN via GSH depletion

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