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Although there are so many drivers of the astrocyte hypertrophic profile in MS, the mechanisms activated by the majority of them seem to be triggered by neuroinflammation and neurodegeneration

o Recent study: 36 lean women with PCOS were given a dose of glucose

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We do note, however, that effect sizes for SEBR in the placebo group (around d = 0.40) were smaller than those assumed during study planning ( d = 1.17) or in the preceding methodological study ( d = 0.70), such that power to detect group differences was smaller than anticipated