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The correct mechanistic statement is subtler and less satisfying: the 3-AR is necessary for the chronic effect but is not the direct molecular target, and part of the acute effect is 3-independent through a route that has not been pinned down

Correlation does not mean causation

When people have a choline deficiency, they are at increased risk for fatty liver disease

doi: 10.1210/er.2008-0021 17 KayVRBloomMSFosterWG

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