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We adjusted all analyses by these variables but this may not have been sufficient to completely control their possible confounding effect
In patients with chest pain (n = 530) and acute coronary syndromes (ACS) (n = 1683), plasma levels of TMAO and its nutrient precursor TML could predict both the near-term (30-day/6-month) and long-term (17-year) risks of CV events (Senthong et al., 2016), heart failure (n = 720) (Tang et al., 2014) and peripheral artery disease (PAD) (n = 935) (Senthong et al., 2016), elevated TMAO levels could predict 5-year mortality and increased plasma TMAO levels were respectively associated with a 4-fold, 3.4-fold and 2.7-fold increased mortality risk

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Adiponectin also promotes HSC activation in vivo and cytokine-induced activation in vitro and shortens the exit time from quiescence in a mammalian target of rapamycin complex 1 (mTORC1)-dependent manner (329)