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26(8 Suppl.), S177S183

J.TwedtD.McKimJ
10.1371/journal.pone.0009367 121 KrgerR.KuhnW.MllerT.WoitallaD.GraeberM.KselS.et al

When to Use Vitamin B12 vs Vitamin B Complex When Vitamin B12 Injections Are Most Appropriate Vitamin B12 injections are most appropriate when there is evidence or strong suspicion of vitamin B12 deficiency

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Lu J, Huang R, Peng Y, Zhang J, Liang K, Wang Y, Feng Y, Wang Z

However, the unbridled and prodigal use of it, especially as a parenteral formulation, seems unjustified, given the lacunae in our knowledge about its antimelanogenic potential, limited clinical evidence favoring its role in skin lightening, and the statutory ban/advisory issued by certain federal agencies