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Additional factors include excessive alcohol consumption, smoking, stress, gastric hyperacidity, diet, genetics, and radiotherapy (Sostres, Gargallo, and Lanas 2013 )

Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease

A.KhoshnoodiJ.Jeddi-TehraniM.ZarnaniA

This does not invalidate the findings but adds a potential source of bias Single-blind only: While the investigator assessing photos was blinded, patients knew whether they received the active serum or saline, which could influence self-reported satisfaction scores No long-term follow-up: The study ended at 6 months

Learning about insulin storage and expiration provides similar principles that apply across injectable medications