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This approach results in nanoparticle accumulation in the cortex and hippocampus of mice after intravenous injection without inducing neurotoxicity or compromising BBB integrity and ultimately leads to attenuated synaptic deficits and tau hyperphosphorylation ( To provide a concise overview of the stimuli-responsive nanoparticle platforms discussed above, Table 1 summarizes their key strengths and weaknesses with respect to AD drug delivery

To view a copy of this licence, visit About this article Cite this article Chen, K., Ma, D., Yang, X