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If there is a dopamine dysfunction associated with neurological disease like ADHD can more worsen the stage of Restless legs syndrome [24-27]
Simsek et al., 2019)
G., Yoo Y
This presents issues in data generalisability to the wider population, which should be addressed in future by the use of more diverse cohorts
The spots fade and the complexion is cooler
Hence, future studies are required to explore the therapeutic potential of caffeine and adenosine receptor antagonists in both nave and dependent rats, at different stages of the disease
