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Curcumin, the main active ingredient in turmeric, has attracted interest due to its wide range of therapeutic benefits that extend beyond its recognized anticancer properties ( Despite its broad mechanistic potential, curcumins clinical translation has been hindered by its inherently low aqueous solubility, rapid metabolism, and poor systemic bioavailabilit (Table 1)

Protein glycation is also one of the main factors contributing to diseases such as diabetes mellitus, carcinoma and cataracts (53,134)

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95% CI, 0.220.46), after adjusting for injury severity [38]

Wood, T

DOI: 10.1002/ana.410420504 23