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Description
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Folate deficiency can have serious side effects, so treatment (especially during early pregnancy) is important
B12 helps the body convert food into energy, which can support metabolic function
Understanding IV B12 therapy helps doctors choose the best treatment for their patients
Benefits, where present, require continued administration nothing about the injection produces a lasting metabolic change once it stops
The peptide typically remains stable for 30-45 days when refrigerated
