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Biguanide-mediated ether lipid synthesis is necessary for a pro-longevity benefit irrespective of bacterial growth or metabolism Previous studies into the biological action of metformin have suggested that biguanides mediate their lifespan-extending properties in the nematode through alterations in growth and metabolism of their bacterial food source (Cabreiro et al., 2013

Results vary by individual and the type of peptide used

doi: 10.1155/2023/6653202

10.5665/sleep.3654 Sleep 148 MichelsL.Schulte-VelsT.SchickM.OGormanR

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Salvianolic acid A, a novel matrix metalloproteinase-9 inhibitor, prevents cardiac remodeling in spontaneously hypertensive rats