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Anemia from another cause, thyroid disease, iron deficiency, folate deficiency, inflammatory disease, and metabolic contributors can all produce overlapping complaints, as can medication effects, sleep disorders, and neurologic conditions
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Most of these involve the stifle (knee) joint, where the cranial cruciate ligament, menisci, and articular cartilage work together and where the majority of canine orthopedic injuries occur: Cranial Cruciate Ligament Disease: The canine equivalent of human ACL tears, extremely common in medium to large breeds
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