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S.TeunissenH.et al

The molecule is small enough to cross the epidermal barrier to some degree, but reaching fibroblasts in the mid-to-deep dermis where the structural work happens requires either injection or a delivery mechanism that bypasses the barrier

Kalbe et al

Pharmaceutical companies that manufacture Bpc-157 as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities

Clinical Safety Profile BPC-157 has been shown to have no significant adverse effects on organ systems in multiple preclinical studieseven when administered in supra-physiological doses