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Description
Intranasal delivery extends the effective CNS half life because the peptide is transported directly along olfactory and trigeminal nerve pathways into cerebrospinal fluid and hippocampal interstitial space, bypassing systemic circulation and hepatic metabolism
They are not exogenous HGH, which he treats as a different intervention with a different risk profile
Structure of the molecule and their specificity towards enzymes is crucial to evaluate the stability of protein and peptide drugs (Bernkop-Schnurch, 1998)
The potential of endogenous neurogenesis for brain repair and regeneration following traumatic brain injury
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Proc Natl Acad Sci USA 102(36):1268412689
