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Lancet 2001;357(9270):17641766

reported the presence of HIF-1 within the muscle fibers of DM patients, the firefly/kidney assay suggested that retinoic acid-inducible gene I (RIG-I), a newly described HIF-induced gene containing HRE, was essential for the transcriptional response to hypoxia after RIG-I removal (187)

The increased potencies of the IGF-I variants may relate to the substantially increased plasma levels of IGF-binding proteins, particularly IGFBP-3, produced by the combined treatment of dexamethasone with IGF-I or the variants

Touloukian RJ, Smith GJ

In the USA, the commonest etiology for ALF is acetaminophen-induced, followed by other drug-induced ALF and viral hepatitis like HBV [1]

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