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However, it is imperative to note that findings from animal models cannot be directly extrapolated to clinical trials in humans

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Clinical studies have also highlighted the therapeutic potential of CSF1R inhibitors in various cancers, including ovarian cancer

Furthermore, because it can interact with neurological pathways, individuals on specific classes of antidepressants or anti-seizure medications must be monitored closely

A systematic review of 11 studies to date (up to 2023) involving 455 patients with FM and 385 controls has shown consistent gut microbiota dysbiosis, with lower microbial diversity, as measured by lower Shannon indices, along with changes in the gut microbiota composition (31).Reported abnormalities include an altered Bacteroidetes/Firmicutes ratio and aberrant abundance of specific taxa, such as members of the family Lachnospiraceae and the genus Prevotella (32)