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By integrating mechanistic and translational insights, this review provides a novel foundation for precision intervention strategies targeting SIRT1 network reprogramming.

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Complexes (14) possess the neutral mononuclear and complex (5) possesses a dinuclear entity

Pulmonary hypertension (PH) is a global health issue characterized by high mortality

Oxidative stress is a significant factor in male infertility, with increasing evidence evaluating the role of antioxidants in mitigating its detrimental effects on sperm function and quality

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