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Persons affected by major depressive disorder manifested acetyl-l-carnitine deficiency compared to age- and sex-matched healthy individuals in two independent study centres

Large-scale, controlled studies are needed before any conclusions can be drawn

Effect of acetyl-L-carnitine in the treatment of painful peripheral neuropathies in HIV+ patients

2015;10(3):e0119479

Given that acetyl-l-carnitine has a neuroprotective action shown in an animal model of ALS [85], it was hypothesised that treatment with acetyl-l-carnitine could help patients with ALS