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Description
Approximately 70% of an oral dose is absorbed in the small intestine, minimally metabolised, and excreted unchanged in urine within 24 hours

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The mucus layer is composed of two components: an inner firmly adherent layer with sparse bacteria and protective secreted peptides with antibacterial functions (e.g., lysozyme and defensins)

Retrieved July 10th, 2024 from Boehringer Ingelheim

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This was joined by a modest outward movement of TM5 (3.6 measured by C carbon of K336 5.66b ), thereby creating an intracellular crevice to accommodate G s coupling 11,12,18