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Gen Comp Endocrinol (2010) 165:54956.10.1016/j.ygcen.2009.07.004 20 BehneDHoferTVon Berwordt-WallrabeRElgerW

Does MTHFR Cause Low Homocysteine

Volume 12

Two classes of thiol peroxidases were first reported in plants in the 1990s: peroxiredoxins (PRX) and the so-called glutathione peroxidases (GPX) (Holland et al

Moreover, neonatal cells appear to compensate for the infection-dependent mitochondrial dysfunction by extramitochondrial ATP production, and proliferating cells are particularly susceptible to apoptosis induced by oxidative stress 105

Glutathione deficiency may promote cancer initiation (by failing to protect DNA from oxidative damage), while elevated glutathione in established tumors may promote cancer progression and treatment resistance (by protecting cancer cells from chemotherapy and radiation) [2][5]