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Outside primary metabolic indications, these mechanisms are also of interest for cardiometabolic risk reduction (such as waist circumference, triglycerides, and blood pressure) and for appetite control during lifestyle-based weight loss plans
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Experimental work in isolated vascular tissue and cell culture models indicates interactions involving regulators such as endothelial nitric oxide synthase, Src kinase signaling, and vascular endothelial growth factor receptor pathways

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