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Insulin resistance and diabetes mellitus in alzheimers disease

LAZ3 protects cardiac remodeling in diabetic cardiomyopathy via regulating miR-21/PPARa signaling

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In rats, TMAO increases with age and causes oxidative stress and inflammation in blood vessels, leading to endothelial (blood vessel lining) dysfunction, which increases the risk of heart disease [12]
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doi: 10.1016/j.biopsych.2004.08.019 26 ArnstenAF
