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10.2174/1570159X11311040002 102 LiJ.ZhangJ.WangM

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It has been hypothesized that the gut microbiome connects the microbiome-gut-brain and neuroimmune-endocrine axes, and this network might influence key components involved in CIPN

Everolimus, an mTOR signaling pathway inhibitor typically used in tumor-targeted therapy, inhibits the mTOR3EBP4 axis, reduces GPX4 expression, and acts synergistically with RSL3 or erastin to induce ccRCC cell ferroptosis (145)

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