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There are eight types of GPX family in mammals (GPX1, GPX2, GPX3, GPX4, GPX5, GPX6, GPX7, GPX8), of which GPX1-4 and GPX6 of mammals are considered to be selenoproteins containing selenium, which have antioxidant functions, and GPX6 is only expressed in the human body (Brigelius-Floh and Maiorino, 2013

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Furthermore, urine may be particularly well suited as a source of biomarkers for IC/BPS because the pathology of this disorder commonly presents as changes in bladder physiology

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Nonneoplastic settings allow for considering downstream Myc effectors, such as PDH, which could be therapeutic

Our laboratorys current technical and resource limitations precluded us from performing comprehensive histological analyses to substantiate our functional and behavioral findings