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The role of MPO and MPO-derived oxidants, particularly HOCl, in NET-mediated microbial killing will be discussed in detail later

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From the study of new phenyl dihydrouracil (PD)-based PROTACs designed by this group, PD-PROTAC 113 (SJ43489) stands out, capable of degrading the LCK protein (DC 50 = 0.8 nM) and inhibiting the cell viability of KOPT-K1 cells with nanomolar potency (IC 50 = 37 nM) 156

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The lentinan can induce an increase in the tolerance of human keratinocytes cells to oxidative damage, and enhance stress resistance, and protective and regenerative activity was demonstrated

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In biology, the cell cycle refers to the sequence of events that a cell must undergo for survival, particularly involving G1, S, G2 and M phases

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Zanardelli, M

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